Publications

Ojha, R., Dittmar, A. A., Severin, G.B., and Koestler, B.J. "Shigella flexneri Diguanylate Cyclases Regulate Virulence." Journal of Bacteriology. in press. 2021.

Koestler, B.J., Ward, C.M., Fisher, C.R., Rajan, A., Maresso, A.W., and Payne, S.M. “Human intestinal enteroids as a model system of Shigella pathogenesis.” Infection and Immunity. doi: 10.1128/IAI.00733-18. April 2019.

Milich, K.M. and Koestler, B.J., Simmons, J.H., Nehete P.N., Di Fiore, A., Williams, L.E., Dudley, J.P., Vanchiere, J., and Payne, S.M. “Methods for detecting Zika virus in feces: a case study in captive squirrel monkeys (Saimiri boliviensis boliviensis).” PLoS ONE. doi: 10.1371/journal.pone.0209391. December 2018.

Koestler, B.J., Fisher, C.R., and Payne, S.M. “Formate promotes Shigella intercellular spread and virulence gene expression.” mBio. doi: 10.1128/mBio.01777-18. September 2018.

*Subject of featured brief in Nature Reviews Microbiology (doi: 10.1038/s41579-018-0105-1)

Koestler, B.J., Ward, C.M., and Payne, S.M. “Shigella pathogenesis modeling with tissue culture assays.” Current Protocols in Microbiology. doi: 10.1002/cpmc.57. August 2018.

Flynn, K., Dowell, G., Johnson, T., Koestler, B.J., Waters, C.M., and Cooper, V. “The evolution of ecological diversity in biofilms of Pseudomonas aeruginosa by altered cyclic diguanylate signaling.” Journal of Bacteriology. doi: 10.1128/jb.00048-16. March, 2016.

Alyaqoub, F.S., Aldhamen, Y.A., Pereira-Hicks, C., Bruger, E.L., Koestler, B.J., Godbehere, S., Waters C.M., and Amalfitano, A. "In vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses Against Extracellular Antigens." Journal of Immunology. doi: 10.4049/jimmunol.1501272. February, 2015.

Yuan, X., Khokhani, D., Wu, X., Yang, F., Biener, G., Koestler, B.J., Raicu, V., He, C., Waters, C.M., Sundin, G.W., Tian, F., and Yang, C.H. " Cross‐talk between a regulatory small RNA, cyclic‐di‐GMP signaling, and flagellar regulator FlhDC for virulence and bacterial behaviors." Environmental Microbiology. doi: 10.1111/1462-2920.13029. August, 2015.

Feirer, N., Xu, J., Allen, K. D., Koestler, B.J., Bruger, E.L., Waters, C.M., White, R.H., and Fuqua, C. “A Pterin-Dependent Signaling Pathway Regulates a Dual Function Diguanylate Cyclase-Phosphodiesterase Controlling Surface Attachment in Agrobacterium tumefaciens.” mBio. doi: 10.1128/mBio.00156-15. June, 2015.

Savage, C.R., Arnold, W.K., Gjevre-Nail, A., Koestler, B.J., Bruger, E.L., Barker, J.R., Waters, C.M., and Stevenson, B. “Intracellular concentrations of Borrelia burgdorferi cyclic di-AMP are not changed by altered expression of the CdaA synthase.” PLoS ONE. doi: 10.1371/journal.pone.0125440. April, 2015.

Flores-Valdez, M.A., Aceves-Sánchez, M.J., Pedroza-Roldán, C., Vega-Domínguez, P.J., Oca, E.P.M., Bravo-Madrigal, J., Laval, F., Daffé, M., Koestler, B.J., and Waters, C.M. “The cyclic di-GMP phosphodiesterase gene Rv1357c/BCG1419c affects BCG pellicle production and in vivo maintenance.” IUBMB Life. doi: 10.1002/iub.1353. February, 2015.

Koestler, B.J. and Waters, C.M. “Intestinal GPS: Bile and bicarbonate control cyclic di-GMP to provide Vibrio cholerae spatial cues within the small intestine.” Gut Microbes. doi: 10.4161/19490976.2014.985989. January, 2015.

Koestler, B.J., Seregin, S.S., Rastall, D.P.W., Aldhamen, Y.A., Godbehere, S., Amalfitano, A., & Waters, C.M. “Stimulating Innate Immunity by in vivo cyclic di-GMP Synthesis using Adenovirus.” Clinical and Vaccine Immunology. doi: 10.1128/CVI.00471-14. November, 2014.

Wu, X., Zeng, Q., Koestler, B.J., Waters, C.M., Sundin, G.W., Hutchins, W., and Yang, C.H. “Deciphering the components that coordinately regulate virulence factors of the soft rot pathogen Dickeya dadantii.” Molecular Plant-Microbe Interactions. doi: 10.1094/MPMI-01-14-0026-R. October, 2014.

Bobrov, A.G., Kirillina, O., Vadyvaloo, V., Koestler, B.J., Hinz, A.K., Mack, D., Waters, C.M., and Perry, R.D. “The Yersinia pestis HmsCDE regulatory system is essential for blockage of the oriental rat flea (Xenopsylla cheopis), a classic plague vector.” Environmental Microbiology. doi: 10.1111/1462-2920.12419. April, 2014.

Koestler, B.J. and Waters, C.M. “Bile Acids and Bicarbonate Inversely Regulate Intracellular Cyclic di-GMP in Vibrio cholerae.” Infection and Immunity. doi: 10.1128/IAI.01664-14. July, 2014.

Hunter, J. L., Severin, G.B., Koestler, B.J., and Waters, C.M. “The Vibrio cholerae diguanylate cyclase VCA0965 has an AGDEF active site and synthesizes cyclic di-GMP.” BMC Microbiology. doi: 10.1186/1471-2180-14-22. February, 2014.

Sambanthamoorthy, K., Luo, C., Pattabhiraman, N., Feng, X., Koestler, B.J., Waters, C.M., and Palys, T. “Identification of Small Molecules Inhibiting Digunylate Cyclases to Control Bacterial Biofilm Development.” Biofouling. doi: 10.1080/08927014.2013.832224. January, 2014.

Bai, Y., Yang, J., Eisele, L.E., Underwood, A.J., Koestler, B.J., Waters, C.M., Metzger, D.W., and Bai, G. “Two DHH subfamily 1 proteins in Streptococcus pneumoniae possess c-di-AMP phosphodiesterase activity and affect bacterial growth and virulence.” Journal of Bacteriology. doi: 10.1128/JB.00769-13. November, 2013.

Koestler, B.J. and Waters, C.M. “Exploring environmental control of cyclic di-GMP signaling in Vibrio cholerae using TELCA.” Applied Environmental Microbiology. doi: 10.1128/AEM.01596-13. September, 2013.

Zhao, X., Koestler, B.J., Waters, C.M., and Hammer, B.K. “Post-transcriptional activation of a diguanylate cyclase by quorum sensing small RNAs promotes biofilm formation in Vibrio cholerae.” Molecular Microbiology. doi: 10.1111/mmi.12325. September, 2013.

Xu, J., Kim, J., Koestler, B.J., Choi, J.H., Waters, C.M., and Fuqua, C. “Genetic Analysis of Agrobacterium tumefaciens Unipolar Polysaccharide Production Reveals Complex Integrated Control of the Motile-to-Sessile Switch.” Molecular Microbiology. doi: 10.1111/mmi.12321. September, 2013.

Agostoni, M., Koestler, B.J., Waters, C.M., Williams, B.L., and Montgomery, B.L. “The Occurrence of Cyclic di-GMP Modulating Output Domains in Cyanobacteria: An Illuminating Perspective.” mBio. doi: 10.1128/mBio.00451-13. August, 2013.

Barker, J.R., Koestler, B.J., Carpenter, V.K., Burdette, D. L., Waters, C.M., and Valdivia, R.H. “STING-dependent recognition of cyclic di-AMP mediates Type I interferon responses during Chlamydia trachomatis infection.” mBio. doi: 10.1128/mBio.00018-13. April, 2013.

Bellows, L.E., Koestler, B.J., Karaba, S.M., Waters, C.M., and Lathem, W.W. “Hfq-dependent, coordinate control of cyclic diguanylate synthesis and catabolism in the plague pathogen Yersinia pestis.” Molecular Microbiology. doi: 10.1111/mmi.12011. November, 2012.

Massie, J. P., Reynolds, E. L., Koestler, B. J., Cong, J.P., Agostoni, M., and Waters, C.M. “Quantification of high-specificity cyclic diguanylate signaling.” Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1115663109. July, 2012.